Osteoporosis drugs linked to weaker bones and increased risk of ‘micro-cracks’

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osteoporosis(NaturalHealth365) A new study has found a medication that’s supposed to offer relief for osteoporosis and weak bones may actually be causing weaker bones! Researchers found a class of drugs called bisphosphonates actually caused a higher risk of ‘micro-cracks’ in the bones of some individuals. The study is out of the Imperial College London and was published in the journal Scientific Reports.

These micro-cracks reduce the mechanical strength of the bone, which is the last thing persons suffering from osteoporosis need. Osteoporosis affects an estimated 200 million persons worldwide, usually those over age 65, causing weak bones to become more fragile and prone to breakage over time.

Bisphosphonates used to treat osteoporosis may actually cause weak bones

In the study, researchers examined bone samples from 16 persons diagnosed with osteoporosis. All had suffered a broken hip, and half had been taking a bisphosphonate for their osteoporosis. The researchers utilized X-rays from the Diamond synchrotron to examine the participants’ bone structure at high resolution.

Much to their alarm, it was found that the bones of some persons taking bisphosphonates had both micro-cracks and reduced mechanical bone strength. The team expressed that there is an urgent need to look further into these findings immediately.

Bisphosphonates could be hindering positive osteoclast functioning

The micro-cracks found were described as similar to the ones that occur when a plastic ruler is flexed. Over time, they weaken the bone and cause it to become more prone to breakage. While bone is regularly renewed throughout life and the healing of micro-cracks can in many cases make the bones stronger, in persons with osteoporosis, the weakening outpaces the body’s ability to renew the bone.

This is due to the presence of osteoclasts, cells that weaken the bone, becoming overactive. These osteoclasts can burrow holes and perforations in the bone in persons with osteoporosis. The most common fracture types in older individuals are in the hip, wrist, ankle and spine.

Bisphosphonates were thought to help persons with osteoporosis by slowing down osteoclast activity and reducing bone weakening and breakage. However, another function of osteoclasts is the removal of old, damaged bone so that new bone can grow. Because of this, in some individuals, these bisphosphonates are actually doing more harm than good.

Researchers advocate alternative approaches to osteoporosis treatment

There are currently around 190 million prescriptions for bisphosphonates issued globally. Researchers previously thought these drugs prevented the risk of bone fracturing by 30 to 50 per cent.  However, the new research indicates there could be deeper problems with the drug for some individuals.

In fact, for some, bisphosphonates may be increasing the risk of bone weakening and fractures.

The research team recommends additional studies on bisphosphonates as soon as possible. They also recommend the development of alternative osteoporosis treatments that work through building new bone instead of just attempting to slow the deterioration of old bone.

Editor’s note: On the NaturalHealth365 Podcast, we reveal the hoax surrounding osteoporosis.  If you know anyone concerned about weakening bones – share this link – it’s a FREE program that can literally save lives.

Also, you may want to check out, Healthy Bones, a great book by Nancy Appleton.





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  • Lokendra singh Rathore

    it s a fact of life :as you age your bones become thinner and lose their density. you can take steps to halt the thinning of your bones https://fatstrapped. com/our-life-in-carbohydrates/

  • Nathan G

    Does anyone realize there is a natural Osteoporosis Week? The National Osteoporosis Foundation is supported by tax dollars. I see a pattern that is very disturbing. Once a condition becomes a money maker-I wonder about the science behind it.

  • Audie Parson

    What happened to calcium rich greens and exercise? Has common sense left. This is a condition caused by a mineral deficiency not a drug deficiency.

  • Carle Lapidos

    Another drug disaster. There seems to be nothing offered for any condition but drugs. Wake up and stop letting them medicate you. Fosamex was and is a horrible solution. It is in our power to strengthen any system with lifestyle modifications.

    • Sue

      Fosamax is a pharmaceutical and connected to calcium deficiency. It shifts calcium around but not efficiently. Why is it that milk consuming continents have calcium deficiency and plant based consumption have no calcium deficiency. Probably because they consume NO dairy. Greens in general contain more efficient calcium in greens. What a waste of time. Calcium from rocks are not absorbable. Swallow a hand full of rocks see how effective it is.

  • Wendy Bays

    I’m seventy next month and many years ago was told I have severe osteoporosis. I took their pills and lots of calcium (with magnesium, which my doc didn’t bother to mention partners with calcium). Each time I had a bone density test, the results were that my bones were still going downhill. They recommended a very expensive once-a-year shot which I declined on. I’ve since heard some people end up with a year of pain from this shot. I have now found what works for me – and the bone density tests show growing bone! It a supplement called strontium, for building bones. It’s not the radioactive type strontium but, a mineral that is as common as dirt and is essential to corals and some other ocean creatures. It works – and now some places are starting to ban it and suppliers are drying up. So sad. Maybe Big Pharma is scaring people by saying we might get the radioactive kind by accident, who knows. I actively work with dogs and have had a few very serious falls on concrete the past couple of years that would have broken bones for many people – but no bones, no hip, wrist or jaw broken. I also take K2 and D3 – and occasionally some calcium.

  • Wendy Bays

    Unfortunately, you seem to have deleted my comment – don’t know why. It was my truth.

  • dmprisk

    Dr. Tomas Levy, M.D’s book Primal Panacea explains that weak bones is Scurvy of the bones, you need vitamin C. Lots of vitamin C. Vitamin C cures everything, but you need to take enough of it and dont’ stop. If you hit bowel tolerance, just back off, but never stop.

  • flavio chab

    I’m MD and was always distrusted about bisphosphonates. I’m proud never prescribed it, but sun as much as possible (Vit D supl) magnesium, more activities and calcium sources. The result was a better densitometry in a year.

  • JT

    I fear I may have hurt a good friendship over this recently after I discovered my friend was going to have Reclast infusions. I about croaked and could not keep silent. I shared with her the research and information on these toxic drugs, not to mention the horrible testimonials that are enough to make one shudder. I was interested to discover that these osteoporosis drugs not only ‘supposedly’ stop the weakening (which is questionable) but they prevent new growth and strengthening from occurring.

  • Georgie Song

    The problem is first the consumers……….they want a “quick fix” and big pharma wanting to deliver. With 200 million sufferers and 190 million taking the drug shows people want a quick fix…….like with so many chronic diseases,…..which is seen also with heart disease and type 2 diabetes..and even with Premarin despite women knowing it cause cancer..instead of Impact exercise which is “SWEAT” to keep healthy bones.
    I had people telling me they rather die than give up meat, or continue to drink soda and just take their insulin.

  • drflora3rd

    Silica turns into bone calcium and knits broken bones within a week or less as long as dairy is not part of the diet because dairy weakens the ends of the broken bones and prolongs healing time. Potassium and magnesium containing foods also turn into bone calcium quickly. Read Biological Transmutation by Dr Kirvran from France.