PQQ an effective tool against arthritis and chronic inflammation
(Naturalhealth365) More than 50 million Americans suffer from arthritis, a painful and potentially debilitating disease. Of course, we all know about the disappointing result, in terms of conventional ‘therapies’ to treat this condition, which is why news about PQQ (Pyrroloquinoline quinone) is so refreshing.
PQQ has been shown to slow down joint deterioration and reduce chronic inflammation present inside the body. And while conventional medicine continues to promote the use of toxic drugs, many researchers believe there is a more effective way to eliminate arthritic pain – without the unwanted side effects of pharmaceutical substances.
The two most common forms of arthritis are triggered by an overactive immune system
Rheumatoid arthritis is precipitated by the release of inflammatory cytokines and enzymes that are unleashed by joint cells – or fibroblast-like synoviocytes – when the immune system (mistakenly) attacks them. The release of these inflammatory molecules is facilitated by a protein complex called NF-kappaB.
These inflaming substances not only damage cartilage and bone – causing pain, swelling and stiffness – but can affect the entire body and increase the risk of heart disease. (Studies have shown that rheumatoid arthritis sufferers are at a 40 percent risk of increased mortality – a frightening statistic indeed).
As for osteoarthritis – the most common form of arthritis – scientists used to believe that it was the result of age-related “wear and tear,” along with declining collagen production. Now, however, researchers suspect that osteoarthritis has an autoimmune component as well.
To manage arthritis symptoms, doctors may prescribe a wide variety of medications – including opiate painkillers, non-steroidal anti-inflammatory drugs, biological response modifiers, anti-TNF- immunosuppressive drugs and corticosteroids. Unfortunately, side effects and adverse reactions from these drugs can be dangerous and even potentially life-threatening.
However, PQQ – an essential nutrient found in plant foods – could be the key to arthritis relief. An extreme antioxidant, PQQ has the amazing ability to create new mitochondria in cells – giving it anti-aging effects, and helping it to protect heart and brain health.
PQQ alleviates joint destruction – safely and effectively
In a study published in Inflammation, researchers used an inflammatory substance to activate the release of harmful cytokines from human joint cells. One group of cells was treated with PQQ, while the other was not.
When the cells were examined, the results were eye-opening.
The untreated group had increased levels of the pro-inflammatory cytokines – which included TNA-a and IL-6 – while the PQQ-treated cells produced substantially smaller amounts.
Researchers also found that PQQ halted the action of NF-kappaB, which helps activate inflammation. And, they discovered that PQQ reduced levels of matrix metalloproteinase – a destructive enzyme that breaks down protective collagen in the joints.
But, wait, there’s more.
In the next phase of the study, researchers injected arthritic mice with PQQ – and found that the PQQ-treated mice had superior protection against inflammatory degeneration and cartilage damage (when compared to mice that had not received the nutrient).
The takeaway is clear: PQQ can slow degeneration of joints and dramatically reduce inflammation.
PQQ shown to combat neurodegenerative disease
But it is not just arthritis that PQQ can benefit.
Studies have shown that this versatile nutrient can inhibit the production of inflammatory chemicals released by microglial cells – the immune system cells of the brain.
This means that PQQ has promising applications for slowing the progress of neurodegenerative diseases – including Alzheimer’s disease, Parkinson’s disease, fibromyalgia, multiple sclerosis, stroke and neuropathy.
Scientists have also found that PQQ has the ability to protect nerve tissues within the brain – and credit it with the ability to prevent oxidative damage after a stroke, as well as to protect against neurotoxicity induced by heavy metal exposure.
Finally, animal studies have shown that PQQ can reverse cognitive impairment – an exciting prospect for all those concerned about many forms of dementia.
How can I increase my intake of PQQ?
PQQ is found in small amounts in all plant foods, but some are richer sources than others.
Celery – with 6.3 micrograms of PQQ to each 100 grams – is a definite high-ringer. Parsley – with 3.4 micrograms – is also a good source. Other PQQ-rich foods include legumes, potatoes, spinach, carrots, cabbage, kiwi fruit and tofu. (naturally, organic varieties would be best to minimize your exposure to unwanted farming chemicals.)
PQQ is also available in supplementary form. Natural health experts and integrative physicians may recommend daily doses of 10 to 20 mg – sometimes in conjunction with CoQ10, another valuable nutrient. Naturally, we suggest that you check with your doctor – before beginning PQQ supplementation.
When it comes to alleviating arthritis, PQQ – which protects cartilage and joints by a variety of mechanisms – really does have a “deep bench.” Studies on PQQ are ongoing – and will likely reveal even more of the disease-fighting potential of this extraordinary nutrient.
Editor’s note: The NaturalHealth365 Store offers an extraordinary product called, “The One” – which includes PQQ, CoQ10, resveratrol plus much more. Click here to order today!*
*And, yes, your purchase helps to support our operations at NaturalHealth365. Thank you.
Sources for this article include:
Food & Nutrition
Natural Health 365
Natural Health 365 is a premium source of trending and popular health-related news, science, testimony & research articles on the most up to date and relevant natural health information. The Food & Nutrition articles found herein are meant to inform and advise our site visitors on eating healthy, nutritious foods and safely using supplements and vitamins to achieve optimal health.
Join thousands of daily visitors staying informed and involved on Natural Health 365! We seek out scientific solutions with proven results and it is our mission to keep you informed! Articles range in topic from the cancer fighting qualities of Olive Oil, to the remarkably high concentration of anti-oxidants found in blueberries, to how to make your own almond milk, to a nutritional comparison of organic vs conventional produce, to an analysis of the health benefits of tree nuts. You can find all of the Food News Articles here
Read Some of Our Most Popular Articles
Artichokes, Olive Oil, Almond Milk, Blueberries
Food News is one of our major post categories on www.naturalhealth365.com and contains over 350 articles that cover a wide range of subjects; including but not limited to…
More Food & Nutrition Articles
Fresh Organic Produce Fights Cancer, Susan G. Komen on Organic Foods, Hemp Seeds for Inflammation, Pau D’Arco For Improved Immunity
In addition to exploring health benefits of certain foods, vitamins and supplements, we also aim to connect healthy eating and balanced consumption of dietary supplements to long-lasting health and adding healthy, happy years to your life. For example, did you know that eating Granny Smith Apples on a regular basis can reduce your chance of building up unhealthy gut yeast? Or that ingesting ground hemp seeds can significantly reduce inflammation throughout the body? Perhaps you didn’t know that Fresh Organic Produce has been found to have higher concentrations of key, cancer-fighting anti-oxidants and vitamins than conventional produce? You can find all of that information and more right here on Natural Health 365.
We’d love to know what you’re thinking! Please join the conversation on Facebook, post comments here on the website and feel free to reach out to us if you have any questions.
Please use and share the articles you find here with your friends, family and peers.